Vacuolar interface dermatitis (VAC, also known as liquefaction degeneration, vacuolar alteration or hydropic degeneration) is a dermatitis with vacuolization at the dermoepidermal junction, with lymphocytic inflammation at the epidermis and dermis.

Pathological and non-pathological bodies is the 'must have' reference website for the biological, medical and biomedical sciences. The site comprises more than 250 bodies, most of which are related to disease processes.

The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal junction by inflammatory cells. Secondary changes of the epidermis and papillary dermis along with type, distribution and density of inflammatory cells are used for the differential diagnoses of the various diseases that exhibit interface changes. Focal hypergranulosis and focal parakeratosis is present. Numerous Civatte bodies are identified. The focal hypergranulosis is not wedge-shaped. There are no pointed rete ridges. There is no basal squamatization.

Sclerotic phase of lichen sclerosus Hypergranulosis, acanthosis, hyperkeratosis, Civatte bodies, pigment incontinence, and follicular plugging can be seen Necrotic keratinocytes can be found both in the dermis and epidermis. There is folliculocentric lichenoid infiltrate at the level of the infundibulum sparing the lower portion, and damage of the outer epithelial sheath of the follicles. Abstract. Eosinophilic apoptotic (necrotic) keratinocytes in the lower epidermis and at the dermoepidermal junction are a feature of many interface dermatoses but are most reliably found in lichen planus. These structures are universally known as Civatte bodies. Nonetheless, they were first described by Raymond Sabouraud in 1912. Se hela listan på librepathology.org Civatte bodies - Spherical, eosinophilic hyaline bodies seen in or below the epidermis in the disease lichen planus.

N.G. EL-LABBAN and; IVOR R.H. KRAMER; Article first published online: 29 JUL 2006. DOI: 10.1111/j.1365-2133.1974.tb06357.x Outlines.

1. J Dermatol. 1980 Oct;7(5):323-33. Electron microscopic studies of porokeratosis Mibelli --Civatte bodies and amyloid deposits in the dermis.

Se hela listan på librepathology.org

Our mission is to provide useful professional information to practicing pathologists and laboratory personnel, through our textbook, in 15 seconds or less. Click here for patient related inquiries. This is a free, no registration website - we are entirely supported by advertising. The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal junction by inflammatory cells. Secondary changes of the epidermis and papillary dermis along with type, distribution and density of inflammatory cells are used for the differential diagnoses of the various diseases that exhibit interface changes. Focal hypergranulosis and focal parakeratosis is present.

The lesions are typically chronic scaly plaques on the face, scalp and ears. Keratin 17-positive Civatte bodies in oral lichen planus—distribution Division of Molecular and Diagnostic Pathology, while type C bodies did not always have a smooth outline, Welcome to the home of pathologicalbodies.com * Pathological Bodies is available on Amazon as a text only pocketbook and as a colour atlas containing both text and illustrations. This website contains the largest web-based collection of pathological and non-pathological bodies and includes a search tool to assist you during your visit. Of the hundreds of bodies listed, two thirds are related 1. J Dermatol. 1980 Oct;7(5):323-33. Electron microscopic studies of porokeratosis Mibelli --Civatte bodies and amyloid deposits in the dermis.
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Dermatopathology Case 116. Low power view of a neural tumour. New - Dermatopathology This is an comprehensive Oral pathology mnemonics course for dental students and dentists of all skill sets.

Lichen planus — there are some overlapping features including interface activity and Civatte body formation.
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Dec 5, 2016 The stroma surrounding the nodules shows foreign body giant cells and Segura S, Requena L. Anatomy and histology of normal subcutaneous fat, Blanc F, Robert C, Fadlallah JP, Moulonguet I, Maurin F, Civatte J.

They are not include apoptotic bodies or Civatte bodies.